CD169 mediates the capture of exosomes in spleen and lymph node
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چکیده
منابع مشابه
Regular Article IMMUNOBIOLOGY CD169 mediates the capture of exosomes in spleen and lymph node
solely due to preferential fluid flow to these areas. Although the circulation half-life of exosomes in blood of wild-type and CD169 mice was similar, exosomes displayed altered distribution in CD169 mice, with exosomes freely accessing the outer marginal zone rim of SIGN-R1 macrophages and F4/80 red pulp macrophages. In the lymph node, exosomes were not retained in the subcapsular sinus of CD1...
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ژورنال
عنوان ژورنال: Blood
سال: 2014
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2013-03-489732